- Title: MR. BRAIN
- Format: Renzoku
- Genre: Comedy, mystery
- Episodes: 8
- Viewership rating: 20.0 (Kanto)
- Broadcast network: TBS
- Broadcast period: 2009-May-23 to 2009-Jul-11
- Air time: Saturday 20:00
- Theme song: JUMP by Van Halen
Tsukumo Ryusuke is a quirky, yet brilliant neuroscientist working for the National Research Institute of Police Science. Wielding a unique perspective and psychology, Tsukumo tackles the nation's most baffling crimes and scandals, going head-to-head with the most brilliant and twisted criminal minds. But his eccentricities and poor social timing can also aggravate people and circumstances, further complicating matters. --TBS
- Kimura Takuya as Tsukumo Ryusuke
- Ayase Haruka as Yuri Kazune
- Mizushima Hiro as Hayashida Toranosuke
- Kagawa Teruyuki as Tanbara Tomomi
- Daichi Mao as Sasa Miharu
- Tanaka Yuji as Natsume Mitsuo
- Tortoise Matsumoto (トータス松本) as Nanba Jotaro
- Hiraizumi Sei as Funaki Junpei
- Shitara Osamu as Kanda Junichi
- Yamazaki Shigenori as Ochi Koichi
- SHIHO as Mariko
- Kinoshita Yukina as the cleaning lady
- Isaka Shunya (井坂俊哉) as Namikoshi Katsumi
- Hayashi Yasufumi as Iwabuchi Kiyoshi
- Kobayashi Katsuya (小林克也) as Seta Ippei
- Ichikawa Ebizo as Takei Kohei (ep1,7-8)
- Sugimoto Tetta as Kojima Hideki (ep1,3,7)
- Takashima Masanobu as Doi Kenzo (ep1)
- Yusuke Santamaria as Funada Tsutomu (ep1)
- Toda Keiko as the host club customer (ep1)
- Hirosue Ryoko (ep1)
- Shiga Kotaro as Tsuchida Goichi (ep1)
- Tsuda Kanji as Komine Kazuhiko (ep1)
- Abe Ryohei as a yakuza (ep1)
- Gackt as Takegami Teijiro (ep2)
- Koyuki as Miyase Kumiko (ep2)
- Matsushige Yutaka as Kishikawa Seiji (ep2)
- Jinbo Satoshi as Tsumura Shusuke (ep2)
- Fukui Hiroaki as Takada Hidekazu (ep2)
- Hirayama Yusuke as Goto Hideki (ep2)
- Ishiguro Hideo as Sugiyama Kozo (ep2)
- Kawamura Yosuke as a detective (ep2,5)
- Onoue Hiroyuki as a member of crime lab (ep2-3,5,7-8)
- Kamenashi Kazuya as Wakui Masakazu (ep3)
- Aibu Saki as Goto Megumi (ep3)
- Koichi Mantaro as Dr. Chihara (ep3)
- Hirayama Hiroyuki as Araki Akio (ep3)
- Shinagawa Toru as Hyuga Shinichi (ep3)
- Okuda Tatsuhito (ep3)
- Sato Takeru as Nakagawa Masaru (ep4-5)
- Kimura Tae as Nakagawa Jun (ep4-5)
- Togi Hideki as Yagi Hitoshi (ep4-5)
- Takaya Yuya (貴山侑哉) as Kinoshita Shoji (ep4)
- David Ito as Nishizaki Minoru (ep5)
- Nakama Yukie as Akiyoshi Kanako (ep5-6)
- Osawa Itsumi (大沢逸美) as Matsushita Yuriko (ep5-6)
- Rokkaku Shinji as Aoyama Koichi (ep5-6)
- Yoshida Yo as Sakamoto Ryoko (ep5-6)
- Kamikawa Takaya as Kitazato Yosuke (ep7-8)
- Mitsuishi Ken as Aizawa Yoshiyuki (ep7-8)
- Hamada Akira as Ozaki Kohei (ep7-8)
- Suzuki Kazuma as Ozaki Shinichiro (ep7-8)
- Shimizu Koji as Kikuchi Daijiro (ep7-8)
- Obayashi Takeshi as Kawase Yozo (ep7-8)
- Yamada Meikyo as Tsuda Yoshikazu (ep7-8)
- Hayashi Tsuyoshi (ep7)
- Katori Shingo as a hijacker (ep8)
- Screenwriter: Makita Mitsuharu, Morishita Yoshiko
- Producer: Ishimaru Akihiko, Iyoda Hidenori
- Director: Fukuzawa Katsuo, Hirakawa Yuichiro, Yamamuro Daisuke
- Music: Kanno Yugo, Izutsu Akio
|01||An Unprecedented Neuroscientific Mystery Activates!!
Eccentric Neuroscientist vs. Serial Demonic Terrorist!!
Teleportation by Brain Usage!?
|02||Eccentric Neuroscientist vs. Beautiful Revived Ghost!!
People Can Be Resurrected via Brain Training!?
|03||Invisible Man Setting Up Serial Murders!!
Brain Training Exposes The Transparent Riddle
|04||Eccentric Neuroscientist vs. Prodigal Pianist!!
A Skeletal Corpse Can Be Resurrected via Playing Cards!?
|05||Eccentric Neuroscientist vs. Beautiful Woman With A Split Personality!!
The Conclusion is an Epiphany!?
|06||Eccentric Neuroscientist vs. The Tragic Multiple Personality Trick!!
Brain Training is a Lie Detector!?
|07||Last Chapter ~ Eccentric Neuroscientist vs. Strongest Left-Brained Man!!
A Time Bomb Within the Brain
|08||Conclusion ~ Farewell To Our Favorite Eccentric Neuroscientist!!
The Final Brain Training is the Method of a Smile
Source: Video Research, Ltd.